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In a very recent research, we reported the identification as well as the characterization of a whole new atypical opioid receptor with unique destructive regulatory Houses in direction of opioid peptides.1 Our outcomes showed that ACKR3/CXCR7, hitherto often known as an atypical scavenger receptor for chemokines CXCL12 and CXCL11, is likewise a wid